America has been grappling with a severe opioid crisis for decades, marked by a rise in opioid misuse, opioid use disorder (OUD), and a staggering increase in overdose deaths. This crisis has evolved through several phases, initially driven by the overprescribing of prescription opioids, followed by surges in heroin use, and most recently, a rapid increase in deaths involving synthetic opioids like fentanyl.